icpeptide@gmail.comThis website has been online since June 2016.

GPS1573 – Hormones

GPS1573 is a potent and dose-dependent peptide antagonist of adrenocorticotrophic (ACTH) -stimulated melanocortin type 2 receptor (MC2R). Along with GPS1574, GPS1773 is an ACTH analogue and as such antagonises MC2R in the nanomolar range. The clinical relevance of GPS1573 is related to Cushing's disease and syndrome, which are both associated with a hypercortisolemic state. Selective antagonism of MC2R using GPS1573 may be a novel treatment modality for Cushing's disease and syndrome.

Technical specification

SequenceH-(nL)P(dF)R(dW)FKAVGKKRR(K/H-(nL)P(dF)R(dW)FKAVGKKRR)-NH2
MW
Purity> 95%
Counter-ionTFA Salts
Delivery formatLyophilized

Price

ProductSizePrice €Price $
CRB1000575-0.5 mg0.5 mg141 €170 $
CRB1000575-1 mg1 mg193 €232 $